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For an adolescent prescribed isotretinoin, which adverse effect should the nurse monitor?

  1. Hypersalivation

  2. Depression

  3. Bradycardia

  4. Hyperreflexia

The correct answer is: Depression

Monitoring for depression is crucial for adolescents prescribed isotretinoin due to its known association with mood changes, including depression and, in some cases, suicidal ideation. Isotretinoin, which is a potent retinoid used primarily for severe acne, can significantly affect mental health, particularly in this age group, who are already prone to mood disorders due to hormonal and social changes. Healthcare providers often emphasize the importance of monitoring both physical and psychological side effects during treatment. Patients and their families should be educated about the potential for mood changes, and any signs of depression should prompt immediate assessment and intervention. Other options, such as hypersalivation, bradycardia, and hyperreflexia, are not commonly associated with isotretinoin therapy and are therefore less important to monitor in this context. While it’s essential to recognize a wide range of possible side effects with any medication, the specific risk of depression linked to isotretinoin makes it particularly critical for nurses and caregivers to maintain vigilance in monitoring the mental health of adolescents undergoing treatment.